Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2375996Generated: November 1, 2026

Phenyl isocyanate → HCID 68965045, compound

https://huagongshe.com/reaction/2375996

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenyl isocyanateHCID 7672—
ReactantHCID 10752245HCID 10752245—
SolventTetrahydrofuranHCID 8028—
ProductHCID 68965045HCID 6896504565.5%

Reaction Steps

A mixture of methyl 6-(4-piperidylamino)nicotinate (0.73 g) and phenyl isocyanate (388 mg) in THF (30 ml) was stirred at ambient temperature for 12 hours. IPE (30 ml) was added to a reaction mixture and the precipitate was collected by filtration to give methyl 6-{[1-(anilinocarbonyl)-4-piperidyl]amino}nicotinate (0.72 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07465731B2
Source datasetuspto-grants-2008_12
ORD IDord-2eb8a6d8e0904ab4a34a80d5ff16ad15
Source noteuspto-grants-2008_12