HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3,5-Trimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole → 4-(4-Bromo-3,5-dimethyl-phenyl)-1,3,5-trimethyl-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3,5-Trimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole | HCID 2795311 | — |
| Reactant | 2-Bromo-5-iodo-1,3-dimethylbenzene | HCID 20748037 | — |
| Product | 4-(4-Bromo-3,5-dimethyl-phenyl)-1,3,5-trimethyl-pyrazole | HCID 86697295 | — |
Reaction Steps
The title compound is prepared from 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-1,3,5-trimethyl-pyrazole and 2-bromo-5-iodo-1,3-dimethyl-benzene following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 7): tR=1.09 min; Mass spectrum (ESI+): m/z=293/295 (Br) [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642585B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-b00ba484e47d4481b0ce0ecc164820ae |
| Source note | uspto-grants-2014_02 |