5-Methylpyridine-3-boronic acid → HCID 86697299, compound

HRID 237626Notes

Reaction equation

HRID 237626 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4](B(O)O)[CH:5]=[N:6][CH:7]=1.[Br:11][C:12]1[C:17]([CH3:18])=[CH:16][C:15](I)=[CH:14][C:13]=1[CH3:20]>>[Br:11][C:12]1[C:17]([CH3:18])=[CH:16][C:15]([C:4]2[CH:5]=[N:6][CH:7]=[C:2]([CH3:1])[CH:3]=2)=[CH:14][C:13]=1[CH3:20]

Participants

3

Reactant 2

HCID 27627085-Methylpyridine-3-boronic acidHCID 207480372-Bromo-5-iodo-1,3-dimethylbenzene

Product 1

HCID 86697299HCID 86697299, compound

Procedure

The title compound is prepared from 5-methyl-pyridine-3-boronic acid and 2-bromo-5-iodo-1,3-dimethyl-benzene following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 9): tR=0.93 min; Mass spectrum (ESI+): m/z=276/278 (Br) [M+H]+.

Sources & evidence

ORD record
ord-cadc2fec94e24b23a7aeec34b9f06cbe
Source dataset
uspto-grants-2014_02
Patent number
US08642585B2

Reaction notes

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