HCID 68708103, compound → HCID 23114021, compound

HRID 2376272Notes

Reaction equation

HRID 2376272 reaction equation
[Br:1][C:2]1[C:3]([CH3:23])=[C:4]([CH3:22])[C:5]2[O:9][C:8](=[O:10])[C:7]([C:12]3[CH:17]=[CH:16][C:15]([CH:18]([CH3:20])[CH3:19])=[CH:14][CH:13]=3)([CH3:11])[C:6]=2[CH:21]=1>C(OCC)(=O)C.CCCCCC>[Br:1][C:2]1[CH:21]=[C:6]([C:7]([C:12]2[CH:13]=[CH:14][C:15]([CH:18]([CH3:20])[CH3:19])=[CH:16][CH:17]=2)([CH3:11])[CH2:8][OH:10])[C:5]([OH:9])=[C:4]([CH3:22])[C:3]=1[CH3:23]

Participants

3

Reactant 1

HCID 68708103HCID 68708103, compound

Product 1

HCID 23114021HCID 23114021, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using 5-bromo-3-(4-isopropylphenyl)-3,6,7-trimethyl-1-benzofuran-2 (3H)-one synthesized in Reference Example 21, the title compound was synthesized in the same manner as in Reference Example 8. Yield 83%. Melting point: 110-111° C. (ethyl acetate-hexane).

Workup

  1. customsynthesized in Reference Example 21

Sources & evidence

ORD record
ord-2ec3b0b7019b4880851c5db53d1caeb2
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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