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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2376327Generated: October 27, 2026

2,3,5-Trimethylphenol → 1-(4-Methylphenyl)-2-(2,3,5-trimethylphenoxy)ethanone

https://huagongshe.com/reaction/2376327

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3,5-TrimethylphenolHCID 12769—
Reactant2-Bromo-4'-methylacetophenoneHCID 69272—
SolventMethanolHCID 887—
Product1-(4-Methylphenyl)-2-(2,3,5-trimethylphenoxy)ethanoneHCID 2311424075%

Reaction Steps

Using 2,3,5-trimethylphenol and 2-bromo-1-(4-methylphenyl)ethanone, the title compound was synthesized in the same manner as in Reference Example 159. Yield 75%. Melting point: 94-95° C. (methanol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07465815B2
Source datasetuspto-grants-2008_12
ORD IDord-2b9b00e1e201450e8cf9b02e8a467058
Source noteuspto-grants-2008_12