HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3,5-Trimethylphenol → 4-Bromo-1-(4-isopropylphenyl)-2-(2,3,5-trimethylphenoxy)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3,5-Trimethylphenol | HCID 12769 | — |
| Reactant | 4-Bromo-2,3,5-trimethylphenol | HCID 3629334 | — |
| Reactant | 2-Bromo-1-(4-(propan-2-yl)phenyl)ethan-1-one | HCID 14042756 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | 4-Bromo-1-(4-isopropylphenyl)-2-(2,3,5-trimethylphenoxy)ethanone | HCID 23114325 | 51% |
Reaction Steps
Using 2,3,5-trimethylphenol, 4-bromo-2,3,5-trimethylphenol was synthesized in the same manner as in Reference Example 23. Using this compound and 2-bromo-1-(4-isopropylphenyl)ethanone obtained in Reference Example 164, the title compound was synthesized in the same manner as in Reference Example 159. Yield 51%. Melting point: 71-72° C. (ethyl acetate-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07465815B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-fe0be915a6014499a2157b0bece4175d |
| Source note | uspto-grants-2008_12 |