4,6,7-Trimethyl-3-(4-methylphenyl)-1-benzofuran → 4,6,7-Trimethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuran

HRID 2376345Notes

Reaction equation

HRID 2376345 reaction equation
[CH3:1][C:2]1[C:7]2[C:8]([C:11]3[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=3)=[CH:9][O:10][C:6]=2[C:5]([CH3:18])=[C:4]([CH3:19])[CH:3]=1>C1COCC1.CO>[CH3:1][C:2]1[C:7]2[CH:8]([C:11]3[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=3)[CH2:9][O:10][C:6]=2[C:5]([CH3:18])=[C:4]([CH3:19])[CH:3]=1

Participants

3

Reactant 1

HCID 231143114,6,7-Trimethyl-3-(4-methylphenyl)-1-benzofuran

Product 1

HCID 231140234,6,7-Trimethyl-3-(4-methylphenyl)-2,3-dihydro-1-benzofuranYield 81%

Reagents, catalysts & solvents 1

HCID 21899815MeOH tetrahydrofuranSolvent

Procedure

Using 4,6,7-trimethyl-3-(4-methylphenyl)-1-benzofuran obtained in Reference Example 191, the title compound was synthesized in the same manner as in Reference Example 144. Yield 81%. Melting point: 65-66° C. (THF-methanol).

Workup

  1. customobtained in Reference Example 191

Sources & evidence

ORD record
ord-8298e06f561a464faeeca6ce39b63f60
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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