HCID 68708254, compound → HCID 68707799, compound

HRID 2376382Notes

Reaction equation

HRID 2376382 reaction equation
C([NH:8][C:9]1[C:10]([CH3:31])=[C:11]([CH3:30])[C:12]2[O:16][CH2:15][CH:14]([C:17]3[CH:22]=[CH:21][C:20]([CH:23]([CH3:25])[CH3:24])=[CH:19][C:18]=3[O:26][CH3:27])[C:13]=2[C:28]=1[CH3:29])C1C=CC=CC=1>C(OCC)(=O)C.CCCCCC>[CH:23]([C:20]1[CH:21]=[CH:22][C:17]([CH:14]2[C:13]3[C:28]([CH3:29])=[C:9]([NH2:8])[C:10]([CH3:31])=[C:11]([CH3:30])[C:12]=3[O:16][CH2:15]2)=[C:18]([O:26][CH3:27])[CH:19]=1)([CH3:25])[CH3:24]

Participants

3

Reactant 1

HCID 68708254HCID 68708254, compound

Product 1

HCID 68707799HCID 68707799, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-benzyl-3-(4-isopropyl-2-methoxyphenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-amine obtained in Reference Example 273, the title compound was synthesized in the same manner as in Reference Example 30. Yield 87%. Melting point: 120-121° C. (ethyl acetate-hexane).

Workup

  1. customobtained in Reference Example 273

Sources & evidence

ORD record
ord-1bc284b48be14b398c8312a315873121
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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