HCID 68707337, compound → HCID 68707870, compound

HRID 2376383Notes

Reaction equation

HRID 2376383 reaction equation
C([NH:8][C:9]1[C:10]([CH3:26])=[C:11]([CH3:25])[C:12]2[O:16][CH2:15][CH:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:13]=2[C:23]=1[CH3:24])C1C=CC=CC=1>C(OCC)(=O)C.CCCCCC>[CH3:24][C:23]1[C:13]2[CH:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH2:15][O:16][C:12]=2[C:11]([CH3:25])=[C:10]([CH3:26])[C:9]=1[NH2:8]

Participants

3

Reactant 1

HCID 68707337HCID 68707337, compound

Product 1

HCID 68707870HCID 68707870, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-benzyl-4,6,7-trimethyl-3-phenyl-2,3-dihydro-1-benzofuran-5-amine obtained in Reference Example 276, the title compound was synthesized in the same manner as in Reference Example 30. Yield 72%. Melting point: 94-95° C. (ethyl acetate-hexane).

Workup

  1. customobtained in Reference Example 276

Sources & evidence

ORD record
ord-0099994d17f74e53971811314aef968e
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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