HCID 23113875, compound → HCID 23114035, compound

HRID 2376392Notes

Reaction equation

HRID 2376392 reaction equation
C([NH:8][C:9]1[C:30]2[CH2:29][CH2:28][CH2:27][CH2:26][C:25]=2[C:12]2[O:13][CH2:14][CH:15]([C:16]3[CH:21]=[CH:20][C:19]([CH:22]([CH3:24])[CH3:23])=[CH:18][CH:17]=3)[C:11]=2[C:10]=1[CH3:31])C1C=CC=CC=1>CCCCCC.C(OCC)(=O)C>[CH:22]([C:19]1[CH:18]=[CH:17][C:16]([CH:15]2[CH2:14][O:13][C:12]3[C:25]4[CH2:26][CH2:27][CH2:28][CH2:29][C:30]=4[C:9]([NH2:8])=[C:10]([CH3:31])[C:11]2=3)=[CH:21][CH:20]=1)([CH3:24])[CH3:23]

Participants

3

Reactant 1

HCID 23113875HCID 23113875, compound

Product 1

HCID 23114035HCID 23114035, compoundYield 76%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-benzyl-3-(4-isopropylphenyl)-4-methyl-2,3,6,7,8,9-hexahydronaphtho[1,2-b]furan-5-amine synthesized in Reference Example 289, the title compound was synthesized in the same manner as in Reference Example 30. Yield 76%. Melting point: 106-107° C. (hexane-ethyl acetate).

Workup

  1. customsynthesized in Reference Example 289

Sources & evidence

ORD record
ord-1bb0e14d851f46f28dfe52f2a4f2da09
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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