HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-6-methylpyrazine → 2-(4-Bromo-3,5-dimethyl-phenyl)-6-methyl-pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-6-methylpyrazine | HCID 26370304 | — |
| Reactant | 2-(4-Bromo-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | HCID 56973136 | — |
| Product | 2-(4-Bromo-3,5-dimethyl-phenyl)-6-methyl-pyrazine | HCID 86697313 | — |
Reaction Steps
The title compound is prepared from 2-bromo-1,3-dimethyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzene and 2-bromo-6-methyl-pyrazine following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 9): tR=1.04 min; Mass spectrum (ESI+): m/z=277/279 (Br) [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642585B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-235190e3dadf489ea9b6c1e16dc4b5a4 |
| Source note | uspto-grants-2014_02 |