2-Bromo-4-methylpyrimidine → 2-(4-Bromo-3,5-dimethyl-phenyl)-4-methyl-pyrimidine

Participants

Role	Name	HCID	Charge
Reactant	2-Bromo-4-methylpyrimidine	HCID 10942928	—
Reactant	2-(4-Bromo-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane	HCID 56973136	—
Product	2-(4-Bromo-3,5-dimethyl-phenyl)-4-methyl-pyrimidine	HCID 86697315	—

Reaction Steps

The title compound is prepared from 2-bromo-1,3-dimethyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzene and 2-bromo-4-methyl-pyrimidine following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 9): tR=1.08 min; Mass spectrum (ESI+): m/z=277/279 (Br) [M+H]+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08642585B2
Source dataset	uspto-grants-2014_02
ORD ID	ord-1cc87e694fa94f71b157827f9716f07b
Source note	uspto-grants-2014_02