Ethyl acetate hexane → HCID 23114243, compound

HRID 2376439Notes

Reaction equation

HRID 2376439 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]2[C:14]3[C:15]([CH3:21])=[C:16]([NH2:20])[C:17]([CH3:19])=[CH:18][C:13]=3[O:12][CH2:11]2)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].CCCCCC.[C:28](OCC)(=[O:30])C>>[CH:1]([C:4]1[CH:5]=[CH:6][C:7]([CH:10]2[C:14]3[C:15]([CH3:21])=[C:16]([NH:20][CH:28]=[O:30])[C:17]([CH3:19])=[CH:18][C:13]=3[O:12][CH2:11]2)=[CH:8][CH:9]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 21226206Ethyl acetate hexaneHCID 23114101HCID 23114101, compound

Product 1

HCID 23114243HCID 23114243, compoundYield 81%

Procedure

Using 3-(4-isopropylphenyl)-4,6-dimethyl-2,3-dihydro-1-benzofuran-5-amine obtained in Reference Example 32, the title compound was synthesized in the same manner as in Reference Example 73. Yield: 81%. Melting point: 193-196° C. (hexane-ethyl acetate).

Workup

  1. customobtained in Reference Example 32

Sources & evidence

ORD record
ord-541f8497bdaa40c68a0ba9e20e3496fd
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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