Ethyl acetate hexane → HCID 23114013, compound

HRID 2376511Notes

Reaction equation

HRID 2376511 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]2[C:14]3[C:15]([CH3:28])=[C:16]([NH:20][C:21](=[O:27])[CH2:22][C:23]([CH3:26])([CH3:25])[CH3:24])[C:17]([CH3:19])=[CH:18][C:13]=3[S:12][CH2:11]2)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].CCCCCC.[C:35](OCC)(=[O:37])[CH3:36]>>[C:35]([C:18]1[C:13]2[S:12][CH2:11][CH:10]([C:7]3[CH:6]=[CH:5][C:4]([CH:1]([CH3:2])[CH3:3])=[CH:9][CH:8]=3)[C:14]=2[C:15]([CH3:28])=[C:16]([NH:20][C:21](=[O:27])[CH2:22][C:23]([CH3:26])([CH3:25])[CH3:24])[C:17]=1[CH3:19])(=[O:37])[CH3:36]

Participants

3

Reactant 2

HCID 21226206Ethyl acetate hexaneHCID 23114340HCID 23114340, compound

Product 1

HCID 23114013HCID 23114013, compoundYield 69%

Procedure

Using N-(3-(4-isopropylphenyl)-4,6-dimethyl-2,3-dihydro-1-benzothien-5-yl)-3,3-dimethylbutanamide obtained in Example 161, the title compound was synthesized in the same manner as in Example 38. Yield: 69%. Melting point: 218-219° C. (hexane-ethyl acetate).

Sources & evidence

ORD record
ord-173c7fee68aa494bba1263b2447788fa
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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