HCID 23114019, compound → HCID 23114020, compound

HRID 2376532Notes

Reaction equation

HRID 2376532 reaction equation
[CH3:1][C:2]([CH3:34])([CH3:33])[CH2:3][C:4]([NH:6][C:7]1[C:8]([CH3:32])=[C:9]([CH3:31])[C:10]2[O:14][CH2:13][CH:12]([C:15]3[CH:20]=[CH:19][C:18]([CH:21]([CH3:28])[CH2:22][C:23](OCC)=[O:24])=[CH:17][CH:16]=3)[C:11]=2[C:29]=1[CH3:30])=[O:5]>C(OCC)(=O)C.CCCCCC>[OH:24][CH2:23][CH2:22][CH:21]([C:18]1[CH:19]=[CH:20][C:15]([CH:12]2[C:11]3[C:29]([CH3:30])=[C:7]([NH:6][C:4](=[O:5])[CH2:3][C:2]([CH3:33])([CH3:1])[CH3:34])[C:8]([CH3:32])=[C:9]([CH3:31])[C:10]=3[O:14][CH2:13]2)=[CH:16][CH:17]=1)[CH3:28]

Participants

3

Reactant 1

HCID 23114019HCID 23114019, compound

Product 1

HCID 23114020HCID 23114020, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using ethyl 3-(4-(5-((3,3-dimethylbutanoyl)amino)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-3-yl)phenyl)butanoate obtained in Example 182, the title compound was synthesized in the same manner as in Example 193. Yield: 85%. Melting point: 145-147° C. (ethyl acetate-hexane).

Sources & evidence

ORD record
ord-1db8e5b42bdd494ebddd975164cc0969
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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