Cyclohexylamine → HCID 23114383, compound

HRID 2376536Notes

Reaction equation

ClC(Cl)(Cl)CO[C:5](=[O:28])[NH:6][C:7]1[C:8]([CH3:27])=[C:9]([CH3:26])[C:10]2[O:14][CH2:13][CH:12]([C:15]3[CH:20]=[CH:19][C:18]([CH:21]([CH3:23])[CH3:22])=[CH:17][CH:16]=3)[C:11]=2[C:24]=1[CH3:25].[CH:31]1([NH2:37])[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1>>[CH:31]1([NH:37][C:5]([NH:6][C:7]2[C:8]([CH3:27])=[C:9]([CH3:26])[C:10]3[O:14][CH2:13][CH:12]([C:15]4[CH:16]=[CH:17][C:18]([CH:21]([CH3:23])[CH3:22])=[CH:19][CH:20]=4)[C:11]=3[C:24]=2[CH3:25])=[O:28])[CH2:36][CH2:35][CH2:34][CH2:33][CH2:32]1

Participants

Reactant 2

HCID 7965Cyclohexylamine

HCID 86618058HCID 86618058, compound

Product 1

HCID 23114383HCID 23114383, compoundYield 92%

Procedure

Using 2,2,2,-trichloroethyl(3-(4-isopropylphenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)carbamate obtained in Example 138 and cyclohexylamine, the title compound was obtained in the same manner as in Example 143.

Sources & evidence

ORD record: ord-7212492450834e9b9ff19e4c78e601c6
Source dataset: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07465815B2

Reaction notes

Loading…