(6-Methoxypyridin-3-yl)boronic acid → HCID 86697328, compound

HRID 237655Notes

Reaction equation

HRID 237655 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6](B(O)O)=[CH:5][N:4]=1.Br[C:13]1[CH:14]=[C:15]([CH3:21])[C:16]([Cl:20])=[C:17]([CH3:19])[CH:18]=1>>[Cl:20][C:16]1[C:17]([CH3:19])=[CH:18][C:13]([C:6]2[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[N:4][CH:5]=2)=[CH:14][C:15]=1[CH3:21]

Participants

3

Reactant 2

HCID 2734368(6-Methoxypyridin-3-yl)boronic acidHCID 27355555-Bromo-2-chloro-m-xylene

Product 1

HCID 86697328HCID 86697328, compound

Procedure

The title compound is prepared from 2-methoxy-pyridine-5-boronic acid and 5-bromo-2-chloro-1,3-dimethyl-benzene following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 7): tR=1.21 min; Mass spectrum (ESI+): m/z=248/250 (Cl) [M+H]+.

Sources & evidence

ORD record
ord-b0c013370cc341b4a106b422621e6064
Source dataset
uspto-grants-2014_02
Patent number
US08642585B2

Reaction notes

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