HCID 23113873, compound → HCID 23113840, compound

HRID 2376555Notes

Reaction equation

HRID 2376555 reaction equation
[CH2:1]([C:8]1(O)[C:12]2[CH:13]=[C:14]([NH:19][C:20](=[O:26])[CH2:21][C:22]([CH3:25])([CH3:24])[CH3:23])[C:15]([CH3:18])=[C:16]([CH3:17])[C:11]=2[O:10][C:9]1([CH3:28])[CH3:27])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(OCC)(=O)C.CCCCCC>[CH2:1]([CH:8]1[C:12]2[CH:13]=[C:14]([NH:19][C:20](=[O:26])[CH2:21][C:22]([CH3:24])([CH3:23])[CH3:25])[C:15]([CH3:18])=[C:16]([CH3:17])[C:11]=2[O:10][C:9]1([CH3:28])[CH3:27])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 1

HCID 23113873HCID 23113873, compound

Product 1

HCID 23113840HCID 23113840, compoundYield 56%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-(3-benzyl-3-hydroxy-2,2,6,7-tetramethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 249, the title compound was synthesized in the same manner as in Example 271. Yield: 56%. Melting point: 186-187° C. (ethyl acetate-hexane).

Sources & evidence

ORD record
ord-400a365a8de5479186fbc852e337cea1
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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