HCID 23113901, compound → HCID 23114408, compound

HRID 2376556Notes

Reaction equation

HRID 2376556 reaction equation
O[C:2]1([CH2:23][C:24]2[CH:29]=[CH:28][C:27]([CH:30]([CH3:32])[CH3:31])=[CH:26][CH:25]=2)[C:6]2[CH:7]=[C:8]([NH:13][C:14](=[O:20])[CH2:15][C:16]([CH3:19])([CH3:18])[CH3:17])[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=2[O:4][C:3]1([CH3:22])[CH3:21]>C(OCC)(=O)C.CCCCCC>[CH:30]([C:27]1[CH:26]=[CH:25][C:24]([CH2:23][CH:2]2[C:6]3[CH:7]=[C:8]([NH:13][C:14](=[O:20])[CH2:15][C:16]([CH3:18])([CH3:17])[CH3:19])[C:9]([CH3:12])=[C:10]([CH3:11])[C:5]=3[O:4][C:3]2([CH3:22])[CH3:21])=[CH:29][CH:28]=1)([CH3:32])[CH3:31]

Participants

3

Reactant 1

HCID 23113901HCID 23113901, compound

Product 1

HCID 23114408HCID 23114408, compoundYield 63%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using N-(3-hydroxy-3-(4-isopropylbenzyl)-2,2,6,7-tetramethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 250, the title compound was synthesized in the same manner as in Example 271. Yield: 63%. Melting point: 130-132° C. (ethyl acetate-hexane).

Sources & evidence

ORD record
ord-ad9a71cecffc43cc8555b0ebd22d8d1c
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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