Tetrahydrofuran hexane → HCID 23113844, compound

HRID 2376583Notes

Reaction equation

[CH3:1][C:2]([CH3:21])([CH3:20])[CH2:3][C:4]([NH:6][C:7]1[C:8]([CH3:19])=[CH:9][C:10]2[O:14][C:13]([CH3:16])([CH3:15])[CH2:12][C:11]=2[C:17]=1[CH3:18])=[O:5].C1C[O:25][CH2:24]C1.CCCCCC>>[CH:24]([C:9]1[C:10]2[O:14][C:13]([CH3:15])([CH3:16])[CH2:12][C:11]=2[C:17]([CH3:18])=[C:7]([NH:6][C:4](=[O:5])[CH2:3][C:2]([CH3:21])([CH3:20])[CH3:1])[C:8]=1[CH3:19])=[O:25]

Participants

Reactant 2

HCID 21883165Tetrahydrofuran hexane

HCID 23113957HCID 23113957, compound

Product 1

HCID 23113844HCID 23113844, compoundYield 85%

Procedure

Using 3,3-dimethyl-N-(2,2,4,6-tetramethyl-2,3-dihydro-1-benzofuran-5-yl)butanamide obtained in Example 339, the title compound was synthesized in the same manner as in Example 20. Yield: 85%. Melting point: 180-181° C. (THF-hexane).

Sources & evidence

ORD record: ord-abe924a113da477e98b072f8727d91ae
Source dataset: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07465815B2

Reaction notes

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