4-Isopropylbenzyl chloride → HCID 23113884, compound

HRID 2376592Notes

Reaction equation

HRID 2376592 reaction equation
[CH:1]([C:3]1[C:11]2[O:10][C:9]([CH3:13])([CH3:12])[CH2:8][C:7]=2[C:6]([CH3:14])=[C:5]([NH:15][C:16](=[O:22])[CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])[C:4]=1[CH3:23])=[O:2].[CH:24]([C:27]1[CH:34]=[CH:33][C:30]([CH2:31]Cl)=[CH:29][CH:28]=1)([CH3:26])[CH3:25]>>[OH:2][CH:1]([C:3]1[C:11]2[O:10][C:9]([CH3:12])([CH3:13])[CH2:8][C:7]=2[C:6]([CH3:14])=[C:5]([NH:15][C:16](=[O:22])[CH2:17][C:18]([CH3:21])([CH3:20])[CH3:19])[C:4]=1[CH3:23])[CH2:31][C:30]1[CH:33]=[CH:34][C:27]([CH:24]([CH3:26])[CH3:25])=[CH:28][CH:29]=1

Participants

3

Reactant 2

HCID 749164-Isopropylbenzyl chlorideHCID 23113844HCID 23113844, compound

Product 1

HCID 23113884HCID 23113884, compoundYield 92%

Procedure

Using N-(7-formyl-2,2,4,6-tetramethyl-2,3-dihydro-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 340 and 4-isopropylbenzyl chloride, the title compound was synthesized in the same manner as in Example 341. Yield: 92%. Amorphous substance.

Sources & evidence

ORD record
ord-fc9a031ed8344a8896d48748606554e6
Source dataset
uspto-grants-2008_12
Patent number
US07465815B2

Reaction notes

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