HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23113844, compound → HCID 23114364, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23113844 | HCID 23113844 | — |
| Reactant | HCID 23114312 | HCID 23114312 | — |
| Reactant | HCID 178424303 | HCID 178424303 | — |
| Solvent | Ethyl acetate hexane | HCID 21226206 | — |
| Product | HCID 23114364 | HCID 23114364 | 24% |
Reaction Steps
Using N-(7-formyl-2,2,4,6-tetramethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethyl-butanamide obtained in Example 340 and 2-methylphenylmagnesium bromide, N-(7-(hydroxy(2-methylphenyl)methyl)-2,2,4,6-tetramethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide was synthesized in the same manner as in Example 239. Using the compound, the title compound was synthesized in the same manner as in Example 271. Yield: 24%. Melting point: 175-176° C. (ethyl acetate-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07465815B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-c79e31f5b62a485d8467fb607c700baf |
| Source note | uspto-grants-2008_12 |