3-(Methylthio)benzeneboronic acid → HCID 69207961, compound

HRID 2376636Notes

Reaction equation

HRID 2376636 reaction equation
F[C:2]1[CH:3]=[C:4]([C:8]2[N:9]=[C:10]([NH2:18])[CH:11]=[C:12]3[C:17]=2[N:16]=[CH:15][CH:14]=[CH:13]3)[CH:5]=[CH:6][CH:7]=1.[CH3:19][S:20]C1C=C(B(O)O)C=CC=1>>[CH3:19][S:20][C:2]1[CH:3]=[C:4]([C:8]2[N:9]=[C:10]([NH2:18])[CH:11]=[C:12]3[C:17]=2[N:16]=[CH:15][CH:14]=[CH:13]3)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 27343833-(Methylthio)benzeneboronic acidHCID 68868568HCID 68868568, compound

Product 1

HCID 69207961HCID 69207961, compound

Procedure

8-(3-Methylsulfanyl-phenyl)-[1,7]naphthyridin-6-ylamine is prepared in an analogous manner to compound D (see Example 22) using 3-methylthiophenyl boronic acid to yield the product, MS (ES+) 268.04

Workup

  1. customto yield the product, MS (ES+) 268.04

Sources & evidence

ORD record
ord-c228ce3a3b474af496d4948d840ec845
Source dataset
uspto-grants-2008_12
Patent number
US07468370B2

Reaction notes

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