HCID 69145081, compound → HCID 178484250, compound

HRID 2376698Notes

Reaction equation

HRID 2376698 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]([C:13]([OH:15])=O)=[N:10][NH:11][CH:12]=2)=[CH:4][CH:3]=1.Cl.Cl.[F:18][C:19]1[CH:20]=[C:21]2[C:26](=[CH:27][C:28]=1[F:29])[N:25]=[C:24]([NH:30][CH2:31][CH2:32][NH:33][CH3:34])[CH:23]=[N:22]2>>[F:18][C:19]1[CH:20]=[C:21]2[C:26](=[CH:27][C:28]=1[F:29])[N:25]=[C:24]([NH:30][CH2:31][CH2:32][N:33]([CH3:34])[C:13]([C:9]1[C:8]([C:5]3[CH:4]=[CH:3][C:2]([F:1])=[CH:7][CH:6]=3)=[CH:12][NH:11][N:10]=1)=[O:15])[CH:23]=[N:22]2

Participants

3

Reactant 2

HCID 69145081HCID 69145081, compoundHCID 178524947HCID 178524947, compound

Product 1

HCID 178484250HCID 178484250, compound

Procedure

The title compound was prepared from 4-(4-fluoro-phenyl)-1H-pyrazole-3-carboxylic acid (43 mg, 0.21 mmol) and N-(6,7-difluoro-quinoxalin-2-yl)-N′-methyl-ethane-1,2-diamine.dihydrochloride, D2 (65 mg, 0.21 mmol) according to the procedure described for Example 1, as a yellow solid (65 mg, 71%).

Sources & evidence

ORD record
ord-e45e8e28ec854c678bc0da4a77c507b2
Source dataset
uspto-grants-2008_12
Patent number
US07468367B2

Reaction notes

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