Peracetic Acid → HCID 86591634, compound

HRID 23767Notes

Reaction equation

HRID 23767 reaction equation
[CH2:1]([N:5]1[C:17]2[C:16]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[N:10]=[CH:9][C:8]=2[N:7]=[CH:6]1)[CH:2]([CH3:4])[CH3:3].C(OO)(=[O:20])C>C1(C)C=CC=CC=1>[CH2:1]([N+:5]1([O-:20])[C:17]2[C:16]3[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=3[N:10]=[CH:9][C:8]=2[N:7]=[CH:6]1)[CH:2]([CH3:4])[CH3:3]

Participants

4

Reactant 2

HCID 6585Peracetic AcidHCID 11424651Deaminoimiquimod

Product 1

HCID 86591634HCID 86591634, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The oxidation of 1-isobutyl-1H-imidazo[4,5-c]quinoline produced in Example 3 is carried out in toluene at 40-45° C. using peracetic acid as oxidant to produce 1-isobutyl-1H-imidazo[4,5-c]quinoline N-oxide. The product is isolated by filtration after addition of a sodium sulfate solution and ammonium hydroxide.

Sources & evidence

ORD record
ord-7cd71137c4cd4066b112bd4c66abb70d
Source dataset
uspto-grants-2005_02
Patent number
US06852861B2

Reaction notes

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