Benzoic acid, 4-fluoro-, ethyl ester → 2-(2-Chloropyridin-4-yl)-1-(4-fluorophenyl)ethanone

HRID 2376722Notes

Reaction equation

HRID 2376722 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][N:3]=1.[F:9][C:10]1[CH:20]=[CH:19][C:13]([C:14](OCC)=[O:15])=[CH:12][CH:11]=1>>[Cl:1][C:2]1[CH:7]=[C:6]([CH2:8][C:14]([C:13]2[CH:19]=[CH:20][C:10]([F:9])=[CH:11][CH:12]=2)=[O:15])[CH:5]=[CH:4][N:3]=1

Participants

3

Reactant 2

HCID 67976Benzoic acid, 4-fluoro-, ethyl esterHCID 772482-Chloro-4-methylpyridine

Product 1

HCID 108578732-(2-Chloropyridin-4-yl)-1-(4-fluorophenyl)ethanone

Procedure

Following a similar procedure to that described in reference example 19, but starting from 2-chloro-4-methylpyridine and ethyl 4-fluorobenzoate, the title compound was obtained.

Sources & evidence

ORD record
ord-2c3703ba762d494d96e96f79e35ad383
Source dataset
uspto-grants-2008_12
Patent number
US07468376B2

Reaction notes

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