1-(6-Methylpyridin-3-yl)-2-(4-pyridyl)ethanone → HCID 178423934, compound

HRID 2376756Notes

Reaction equation

HRID 2376756 reaction equation
[CH3:1][C:2]1[N:7]=[CH:6][C:5]([C:8](=O)[CH2:9][C:10]2[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=2)=[CH:4][CH:3]=1.[NH2:17][C:18]1[NH:19][N:20]=[C:21]([CH3:23])[CH:22]=1>>[CH3:23][C:21]1[C:22]2[C:18](=[N:17][C:8]([C:5]3[CH:6]=[N:7][C:2]([CH3:1])=[CH:3][CH:4]=3)=[C:9]([C:10]3[CH:15]=[CH:14][N:13]=[CH:12][CH:11]=3)[C:8]=2[C:5]2[CH:6]=[N:7][C:2]([CH3:1])=[CH:3][CH:4]=2)[NH:19][N:20]=1

Participants

3

Reactant 2

HCID 631555021-(6-Methylpyridin-3-yl)-2-(4-pyridyl)ethanoneHCID 178418690HCID 178418690, compound

Product 1

HCID 178423934HCID 178423934, compoundYield 24%

Procedure

Following a similar procedure to that described in example 1 method A, but using 1-(6-methylpyridin-3-yl)-2-(4-pyridyl)ethanone (obtained in reference example 13) instead of 1-(4-fluorophenyl)-2-(4-pyridyl)ethanone and 3-amino-5-methyl-2H-pyrazole instead of 3-amino-2H-pyrazole, the title compound was obtained (yield: 24%).

Sources & evidence

ORD record
ord-b51fdee7d0ae49078619c0acb1dffc49
Source dataset
uspto-grants-2008_12
Patent number
US07468376B2

Reaction notes

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