Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2376761Generated: November 1, 2026

Isopropyl isocyanate → HCID 68445793, compound

https://huagongshe.com/reaction/2376761

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropyl isocyanateHCID 61277—
Reactant2-(2-Aminoethyl)-4,6-bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridineHCID 67013573—
SolventDimethylformamideHCID 6228—
ProductHCID 68445793HCID 6844579350%

Reaction Steps

To a solution of 2-(2-aminoethyl)-4,6-bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine (0.06 g, 0.15 mmol, obtained in example 90) in DMF (1 mL), isopropylisocyanate (0.02 g, 0.18 mmol) was added under argon atmosphere. This was stirred at room temperature for 2 days. The solvent was concentrated again and diethyl ether was added to the residue obtained. The solvent was concentrated, to afford 38 mg of title compound in solid form (yield: 50%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07468376B2
Source datasetuspto-grants-2008_12
ORD IDord-5c59ac55329d464b82edacdf4f22a20d
Source noteuspto-grants-2008_12