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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2376773Generated: October 30, 2026

Benzyl chloroformate → N-Benzyloxycarbonyl-[5-(2-methylsulfanylpyrimidin-4-yl)-6-(3-trifluoromethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]amine

https://huagongshe.com/reaction/2376773

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl chloroformateHCID 10387—
ReactantHCID 178503412HCID 178503412—
ProductN-Benzyloxycarbonyl-[5-(2-methylsulfanylpyrimidin-4-yl)-6-(3-trifluoromethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]amineHCID 68446171—

Reaction Steps

Following a similar procedure to that described in example 245, but starting from 3-amino-5-[2-(methylsulfanyl)pyrimidin-4-yl]-6-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridine (obtained in example 123) and benzyl chloroformate, the desired compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07468376B2
Source datasetuspto-grants-2008_12
ORD IDord-da3ac6ab25e14e03bbc2032aff1e8f4b
Source noteuspto-grants-2008_12