2-Bromo-4-methylpyridine → HCID 86697352, compound

HRID 237678Notes

Reaction equation

HRID 237678 reaction equation
[Br:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5](B2OC(C)(C)C(C)(C)O2)=[CH:4][C:3]=1[CH3:18].Br[C:20]1[CH:25]=[C:24]([CH3:26])[CH:23]=[CH:22][N:21]=1>>[Br:1][C:2]1[C:3]([CH3:18])=[CH:4][C:5]([C:20]2[CH:25]=[C:24]([CH3:26])[CH:23]=[CH:22][N:21]=2)=[CH:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 27340872-Bromo-4-methylpyridineHCID 569731362-(4-Bromo-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Product 1

HCID 86697352HCID 86697352, compound

Procedure

The title compound is prepared from 2-bromo-1,3-dimethyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzene and 2-bromo-4-methyl-pyridine following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 7): tR=0.90 min; Mass spectrum (ESI+): m/z=276/278 (Br) [M+H]+.

Sources & evidence

ORD record
ord-e5f3ab8e2bfe46fd96ed4ecf2c386252
Source dataset
uspto-grants-2014_02
Patent number
US08642585B2

Reaction notes

Loading…