2-Bromo-4,6-dimethylpyridine → HCID 86697354, compound

HRID 237680Notes

Reaction equation

HRID 237680 reaction equation
[Cl:1][C:2]1[C:7]([CH3:8])=[CH:6][C:5](B2OC(C)(C)C(C)(C)O2)=[CH:4][C:3]=1[CH3:18].Br[C:20]1[CH:25]=[C:24]([CH3:26])[CH:23]=[C:22]([CH3:27])[N:21]=1>>[Cl:1][C:2]1[C:3]([CH3:18])=[CH:4][C:5]([C:20]2[CH:25]=[C:24]([CH3:26])[CH:23]=[C:22]([CH3:27])[N:21]=2)=[CH:6][C:7]=1[CH3:8]

Participants

3

Reactant 2

HCID 149751952-Bromo-4,6-dimethylpyridineHCID 532171282-(4-Chloro-3,5-dimethylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Product 1

HCID 86697354HCID 86697354, compound

Procedure

The title compound is prepared from 2-chloro-1,3-dimethyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzene and 2-bromo-4,6-dimethyl-pyridine following a procedure analogous to that described in Step 1 of Intermediate 56. LC (method 7): tR=0.89 min; Mass spectrum (ESI+): m/z=246/248 (Cl) [M+H]+.

Sources & evidence

ORD record
ord-3c8f54c8fc9545e0a508c3878db6c120
Source dataset
uspto-grants-2014_02
Patent number
US08642585B2

Reaction notes

Loading…