o-Iodonitrobenzene → HCID 21099425, compound

HRID 2377011Notes

Reaction equation

I[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].[F:11][C:12]1[CH:17]=[C:16]([F:18])[CH:15]=[CH:14][C:13]=1[CH2:19][CH2:20][C:21]1[CH:26]=[CH:25][C:24]([S:27](C2C=CC=CC=2)(=[O:29])=[O:28])=[CH:23][CH:22]=1>>[F:11][C:12]1[CH:17]=[C:16]([F:18])[CH:15]=[CH:14][C:13]=1/[CH:19]=[CH:20]/[C:21]1[CH:26]=[CH:25][C:24]([S:27]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=2[N+:8]([O-:10])=[O:9])(=[O:29])=[O:28])=[CH:23][CH:22]=1

Participants

Reactant 2

HCID 69115o-Iodonitrobenzene

HCID 21099424HCID 21099424, compound

Product 1

HCID 21099425HCID 21099425, compound

Procedure

2,4-Difluoro-1-((E)-2-{4-[(2-nitrophenyl)sulfonyl]phenyl}vinyl)benzene was prepared according to the method of Example 135 Step 2 using 2-iodonitrobenzene and Intermediate 2.

Sources & evidence

ORD record: ord-ad3c4ddd19e44aef83b2eeed578e8e10
Source dataset: uspto-grants-2008_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07468393B2

Reaction notes

Loading…