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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2377115Generated: October 31, 2026

4-Methylmorpholine → HCID 15957084, compound

https://huagongshe.com/reaction/2377115

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylmorpholineHCID 7972—
Reactant2-Chloro-4,6-dimethoxy-1,3,5-triazineHCID 18450—
ReactantN-methylhydroxylamine hydrochlorideHCID 77906—
ReactantHCID 59855843HCID 59855843—
ProductHCID 15957084HCID 15957084—

Reaction Steps

The title compound was prepared as in example 116, step 3, using 1-(4-fluorobenzyl)-3-{[(1R)-1-phenylethoxy]methyl}-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid, 2-chloro-4,6-dimethoxy-1,3,5-triazine, N-methyl morpholine, and N-methyl hydroxylamine hydrochloride. 1H NMR (400 MHz, DMSO-D6) δ ppm 1.35 (d, J=6.32 Hz, 3H) 3.33 (s, 3H) 4.50 (s, 2H) 4.55 (q, J=6.57 Hz, 1H) 5.53 (s, 2H) 7.16 (t, J=8.84 Hz, 2H) 7.29 (td, J=5.49, 3.16 Hz, 1H) 7.34-7.39 (m, 6H) 7.82 (s, 1H) 7.98 (s, 1H) 8.89 (s, 1H)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07468375B2
Source datasetuspto-grants-2008_12
ORD IDord-cf4e07158423490492364b9b296afc8c
Source noteuspto-grants-2008_12