HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Phenoxybenzaldehyde → Cyanide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Phenoxybenzaldehyde | HCID 38284 | — |
| Reactant | gamma-Cyhalothrin | HCID 6440554 | — |
| Reactant | (1RS)-cis-3-(Z-2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethylcyclopropanecarbonyl chloride | HCID 11334477 | — |
| Product | Cyanide | HCID 5975 | — |
| Product | gamma-Cyhalothrin | HCID 6440554 | — |
Reaction Steps
Surprisingly, the applicants have also found it is possible to make gamma-cyhalothrin in a process wherein steps b) and c) can be combined (in a one-pot process), that is a process for the preparation of gamma-cyhalothrin in which 1R cis-Z 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl cyclopropanecarboxylic acid chloride (III) is reacted with 3-phenoxy benzaldehyde (IV) and a source of cyanide to give gamma-cyhalothrin (I).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07468453B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-0f901e5ada364bbf86243befb2b08010 |
| Source note | uspto-grants-2008_12 |