反应详情

温度

50 °C

5.4 g (14 mmol) of methyl 6-benzyloxy-5-tert-butyl-4′-methyl-3-biphenylcarboxylate (Example 1, d) are dissolved in 100 mL of acetonitrile. 6 mL (41 mmol) of trimethylsilyl iodide are added and the mixture is heated at 50° C. for 24 hours. After extraction, the residue obtained is subjected to esterification conditions similar to those of Example 1 b, and the residue obtained is purified by chromatography. A white solid is obtained (m=1.6 g, yield=36%; m.p.=105° C.).

1. extractionAfter extraction
2. customthe residue obtained
3. customthe residue obtained
4. customis purified by chromatography
5. customA white solid is obtained (m=1.6 g, yield=36%; m.p.=105° C.)