4-Formylbenzoic acid → 4-[(E)-3-(5-tert-Butyl-6-isobutoxy-4'-methyl-3-biphenylyl)-3-oxopropenyl]benzoic Acid

HRID 2377205Notes

Reaction equation

HRID 2377205 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([C:23](=[O:25])[CH3:24])[CH:8]=[C:9]([C:16]2[CH:21]=[CH:20][C:19]([CH3:22])=[CH:18][CH:17]=2)[C:10]=1[O:11][CH2:12][CH:13]([CH3:15])[CH3:14])([CH3:4])([CH3:3])[CH3:2].[C:26]([C:29]1[CH:36]=[CH:35][C:32]([CH:33]=O)=[CH:31][CH:30]=1)([OH:28])=[O:27]>>[C:1]([C:5]1[CH:6]=[C:7]([C:23](=[O:25])/[CH:24]=[CH:33]/[C:32]2[CH:35]=[CH:36][C:29]([C:26]([OH:28])=[O:27])=[CH:30][CH:31]=2)[CH:8]=[C:9]([C:16]2[CH:17]=[CH:18][C:19]([CH3:22])=[CH:20][CH:21]=2)[C:10]=1[O:11][CH2:12][CH:13]([CH3:15])[CH3:14])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 120884-Formylbenzoic acidHCID 120848241-(5-tert-Butyl-6-isobutoxy-4'-methyl-3-biphenylyl)ethanone

Product 1

HCID 120848254-[(E)-3-(5-tert-Butyl-6-isobutoxy-4'-methyl-3-biphenylyl)-3-oxopropenyl]benzoic AcidYield 50%

Procedure

In a similar manner to that of Example 2 b, by reacting 1 g (2.9 mmol) of 1-(5-tert-Butyl-6-isobutoxy-4′-methyl-3-biphenylyl)ethanone with 400 mg (2.6 mmol) of 4-carboxybenzaldehyde. A yellow solid is obtained (m=700 mg; yield=50%; m.p.=243° C.).

Workup

  1. customA yellow solid is obtained (m=700 mg; yield=50%; m.p.=243° C.)

Sources & evidence

ORD record
ord-5aed51f024414f0ab7d5dfa8f8b5ff9c
Source dataset
uspto-grants-2008_12
Patent number
US07468457B2

Reaction notes

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