Potassium Carbonate → HCID 67020708, compound

Participants

Reaction Steps

In a manner similar to that of Example 2 b, by reacting 1.3 g (3.4 mmol) of 3-acetyl-5,5,8,8-tetramethyl-5,6,7,8-tetrahydro-1-naphthyl 1,1,1-trifluoromethanesulfonate with 600 mg (4.4 mmol) of 4-tert-butylphenylboronic acid, 450 mg (10.8 mmol) of lithium chloride, 4.6 mL (9.2 mmol) of 2 M potassium carbonate solution and 220 mg of tetrakis(triphenylphosphine)palladium. The desired product is obtained in the form of white crystals (m=812 mg; yield=66%; m.p.=134° C.).

Provenance & Evidence