Epichlorohydrin → 4-[4-(Oxiran-2-ylmethoxy)phenyl]oxane

HRID 237739Notes

Reaction equation

HRID 237739 reaction equation
[O:1]1[CH2:6][CH2:5][CH:4]([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[CH2:3][CH2:2]1.[CH2:14]([CH:16]1[O:18][CH2:17]1)Cl>>[O:18]1[CH2:17][CH:16]1[CH2:14][O:13][C:10]1[CH:9]=[CH:8][C:7]([CH:4]2[CH2:5][CH2:6][O:1][CH2:2][CH2:3]2)=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 7835EpichlorohydrinHCID 227373584-(Oxan-4-yl)phenol

Product 1

HCID 866402314-[4-(Oxiran-2-ylmethoxy)phenyl]oxane

Procedure

The title compound was prepared from 4-(tetrahydropyran-4-yl)-phenol and epichlorohydrin according to the procedures employed for the preparation of the compound in Step 1 of Example 2.

Workup

  1. customemployed for the preparation of the compound in Step 1 of Example 2

Sources & evidence

ORD record
ord-a48c816b47654993a4b9835e6b2f3794
Source dataset
uspto-grants-2014_02
Patent number
US08642603B2

Reaction notes

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