Epichlorohydrin → 1,2,2,6,6-Pentamethyl-4-(4-oxiranylmethoxy-phenyl)-piperidine

HRID 237747Notes

Reaction equation

HRID 237747 reaction equation
[CH3:1][N:2]1[C:7]([CH3:9])([CH3:8])[CH2:6][CH:5]([C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=2)[CH2:4][C:3]1([CH3:18])[CH3:17].[CH2:19]([CH:21]1[O:23][CH2:22]1)Cl>>[CH3:1][N:2]1[C:7]([CH3:9])([CH3:8])[CH2:6][CH:5]([C:10]2[CH:11]=[CH:12][C:13]([O:16][CH2:19][CH:21]3[CH2:22][O:23]3)=[CH:14][CH:15]=2)[CH2:4][C:3]1([CH3:18])[CH3:17]

Participants

3

Reactant 2

HCID 7835EpichlorohydrinHCID 196012004-(1,2,2,6,6-Pentamethyl-piperidin-4-yl)-phenol

Product 1

HCID 196012081,2,2,6,6-Pentamethyl-4-(4-oxiranylmethoxy-phenyl)-piperidine

Procedure

The title compound was prepared from 4-(1,2,2,6,6-pentamethyl-piperidin-4-yl)-phenol and epichlorohydrin according to the procedures employed for the preparation of the compound in Step 1 of Example 2.

Workup

  1. customemployed for the preparation of the compound in Step 1 of Example 2

Sources & evidence

ORD record
ord-59727610d29e406a9aeea07b405e7468
Source dataset
uspto-grants-2014_02
Patent number
US08642603B2

Reaction notes

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