HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Benzyloxy-4-(3,3-dimethyl-cyclohex-1-enyl)-benzene → 4-(3,3-Dimethyl-cyclohexyl)-phenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Benzyloxy-4-(3,3-dimethyl-cyclohex-1-enyl)-benzene | HCID 68524708 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-(3,3-Dimethyl-cyclohexyl)-phenol | HCID 68529105 | 102.4% |
Reaction Steps
To 1-benzyloxy-4-(3,3-dimethyl-cyclohex-1-enyl)-benzene (4.3 g, 16.4 mmol) in MeOH (50 mL) and EtOAc (50 mL) was added 10% Pd/C (0.67 g) under N2. This mixture was stirred under H2 (1 atm) overnight. The reaction mixture was filtered through celite. The filtrate was concentrated to give the title compound as a white solid (3.43 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642603B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-7dfa238d8d274833ae53a7002e2ed873 |
| Source note | uspto-grants-2014_02 |