HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-Methoxy-benzyl)-cyclohexanone → 7-methoxy-2,3,4,4a,9,9a-hexahydro-1H-fluorene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-Methoxy-benzyl)-cyclohexanone | HCID 14868016 | — |
| Reactant | 7-methoxy-2,3,4,9-tetrahydro-1H-fluorene | HCID 68525913 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol, mixt. with methanol | HCID 18681192 | — |
| Product | 7-methoxy-2,3,4,4a,9,9a-hexahydro-1H-fluorene | HCID 68524779 | — |
Reaction Steps
2-(3-Methoxy-benzyl)-cyclohexanone was converted to 7-methoxy-2,3,4,9-tetrahydro-1H-fluorene in accordance with the procedure of U.S. Pat. No. 3,743,663, followed by hydrogenation (Pd/C, MeOH/EtOH, H2, 1 atm) to obtain 7-methoxy-2,3,4,4a,9,9a-hexahydro-1H-fluorene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642603B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-db771e7933a44babad2406ed2977bc71 |
| Source note | uspto-grants-2014_02 |