Ethyl 2,2-dimethylhex-5-enoate → N-({[1-(But-3-en-1-yl)cyclopropyl]methoxy}carbonyl)-3-methyl-L-valine

Participants

Role	Name	HCID	Charge
Reactant	Ethyl 2,2-dimethylhex-5-enoate	HCID 14906730	—
Reactant	(S)-2-((((2,2-Dimethylhex-5-en-1-yl)oxy)carbonyl)amino)-3,3-dimethylbutanoic acid	HCID 45379499	—
Product	N-({[1-(But-3-en-1-yl)cyclopropyl]methoxy}carbonyl)-3-methyl-L-valine	HCID 45379500	—

Reaction Steps

N-{[(1-But-3-en-1-ylcyclopropyl)methoxy]carbonyl}-3-methyl-L-valine was prepared according to the procedure for N-{[(2,2-dimethylhex-5-enyl)oxy]carbonyl}-3-methyl-L-valine (Steps 2 and 3) by using ethyl 1-but-3-en-1-ylcyclopropanecarboxylate_instead of ethyl 2,2-dimethylhex-5-enoate in Step 2. LRMS (ESI) m/z 284.3 [(M+H)+; calcd for C15H26NO4: 284.2].

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07470664B2
Source dataset	uspto-grants-2008_12
ORD ID	ord-fa17572010e045199a0204fdc27c7ce7
Source note	uspto-grants-2008_12