Formaldehyde → HCID 10313814, compound

Participants

Role	Name	HCID	Charge
Reactant	Formaldehyde	HCID 712	—
Reactant	1H-Pyrrolo(2,3-b)pyridine	HCID 9222	—
Reactant	Sodium Acetate	HCID 517045	—
Reactant	2-(Piperazin-1-yl)pyridine-3-carbonitrile	HCID 2737203	—
Product	HCID 10313814	HCID 10313814	—

Reaction Steps

1H-pyrrolo[2,3-b]pyridine (47 mg, 0.40 mmol), 2-(1-piperazinyl)nicotinonitrile (75 mg, 0.48 mmol), sodium acetate (72 mg, 0.53 mmol), and formaldehyde (0.48 mmol) were processed as described in Example 18 to provide the title compound. 1H NMR (300 MHz, DMSO-d6) δ 2.57 (m, 4H) 3.50 (m, 4H) 3.84 (s, 2H) 6.63 (m, 2H) 6.81 (m, 1H) 7.32 (m, 1H) 7.52 (m, 1H) 7.77 (m, 1H) 7.90 (m, 1H). (ESI) m/z 319 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07470691B2
Source dataset	uspto-grants-2008_12
ORD ID	ord-5494ec24045340238ab075b15273aaa3
Source note	uspto-grants-2008_12