HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 10018365, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 1-(2-Pyridyl)piperazine | HCID 94459 | — |
| Reactant | 2-(Chloromethyl)-[1,3]thiazolo[5,4-b]pyridine | HCID 14204207 | — |
| Product | HCID 10018365 | HCID 10018365 | — |
Reaction Steps
The product from Example 38A (150 mg, 0.81 mmol), 1-(2-pyridinyl)piperazine (160 mg, 0.98 mmol), and D1 EA (280 μL, 1.6 mmol) were processed as described in Example 38B to provide the title compound. 1H NMR (300 MHz, DMSO-d6) δ 2.80 (m, 4H) 3.55 (m, 4H) 4.04 (s, 2H) 6.63 (m, 1H) 6.81 (m, 1H) 7.53 (m, 2H) 8.11 (m, 1H) 8.33 (dd, J=8.14, 1.70 Hz, 1H) 8.59 (dd, J=4.58, 1.53 Hz, 1H); (ESI) m/z 312 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07470691B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-e5bd94539ec342afb2e75012ed99f4af |
| Source note | uspto-grants-2008_12 |