Tert-Butylamine → HCID 23135960, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-bromoethyl phthalimide (20 g, 2 equiv), tert-butylamine (41 ml, 1 equiv) and potassium carbonate (10.86 g, 2 equiv) in dimethylformamide (200 ml) was heated to 50° C. for 48 hours. Solvent was evaporated and the residue partitioned between dichloromethane and water. The organic phase was dried (K2CO3) and solvent removed to afford the title compound as an orange solid (18.93 g). 1H-NMR (CDCl3), δ 1.05 (9H, s), 2.85 (2H, t), 3.77 (2H, t), 7.72 (2H, m), 7.85 (2H, m)

Provenance & Evidence