Epichlorohydrin → 2-((4-(Trifluoromethyl)phenoxy)methyl)oxirane

HRID 237778Notes

Reaction equation

[F:1][C:2]([F:11])([F:10])[C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1.[CH2:12]([CH:14]1[O:16][CH2:15]1)Cl>>[F:1][C:2]([F:10])([F:11])[C:3]1[CH:4]=[CH:5][C:6]([O:9][CH2:12][CH:14]2[CH2:15][O:16]2)=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 7835Epichlorohydrin

HCID 678744-(Trifluoromethyl)phenol

Product 1

HCID 222827522-((4-(Trifluoromethyl)phenoxy)methyl)oxirane

Procedure

The title compound was prepared from 4-trifluromethyl-phenol and epichlorohydrin employing the procedures as set forth in Step 1 of Example 2.

Sources & evidence

ORD record: ord-9153705c12994b5c86d3a1ad30a38f9b
Source dataset: uspto-grants-2014_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08642603B2

Reaction notes

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