HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Isothiocyanatophenyl)ethanone → HCID 59857486, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Isothiocyanatophenyl)ethanone | HCID 242779 | — |
| Reactant | 2-(2-Tert-butylphenoxy)pyridin-3-amine | HCID 28605427 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 59857486 | HCID 59857486 | 19.7% |
Reaction Steps
127.15 mg (0.525 mmol) of 1b were mixed with 92.16 mg (0.525 mmol) of 1-(4-isothiocyanatophenyl)ethanone, 5 mL of CH2Cl2 and 6.61 mg (0.052 mmol) of DMAP and refluxed under Argon for 72 h. 225a was filtered and purified by crystallization in MeOH to yield 43.3 mg of an off-white solid used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07470712B2 |
| Source dataset | uspto-grants-2008_12 |
| ORD ID | ord-9b411c9c9f46430e93fcea481159f343 |
| Source note | uspto-grants-2008_12 |