1-Phenyl-1-propanone → 1,2-Propanedione, 1-phenyl-, 2-oxime

HRID 2377965Notes

Reaction equation

HRID 2377965 reaction equation
C(C1C=CC=CC=1)(=O)CC.[C:11]1([C:17](=[O:23])[C:18](=[N:21][OH:22])[CH2:19]C)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[C:11]1([C:17](=[O:23])[C:18](=[N:21][OH:22])[CH3:19])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

3

Reactant 2

HCID 71481-Phenyl-1-propanoneHCID 713398922-(Hydroxyimino)-1-phenylbutan-1-one

Product 1

HCID 63990241,2-Propanedione, 1-phenyl-, 2-oximeYield 84%

Procedure

Propiophenone (0.100 g, 0.746 mmol) was reacted as described for the synthesis of 1-phenyl-butane-1,2-dione 2-oxime and gave the title material (0.103 g, 84%). HPLC 98.7% (220 nm), LCMS (+ESI, M+H+) m/z 279; 1H NMR (400 MHz, methanol-d4) δ (ppm): 2.09 (3H, s), 7.42 (2H, m), 7.55 (1H, m), 7.89 (2H, d, J=7.1 Hz).

Sources & evidence

ORD record
ord-9c4077361e3b4c8989bf3b77a6081c95
Source dataset
uspto-grants-2008_12
Patent number
US07470713B2

Reaction notes

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