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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2377983Generated: November 1, 2026

Trifluoroacetic acid → HCID 23146261, compound

https://huagongshe.com/reaction/2377983

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 86625768HCID 86625768—
SolventDichloromethaneHCID 6344—
ProductHCID 23146261HCID 2314626129.3%

Reaction Steps

(RS)-2-Benzooxazol-2-ylmethyl-piperidine-1-carboxylic acid tert butyl ester (0.50 g) in dichloromethane (8 ml) was cooled (ice-bath) and trifluoroacetic acid (2 ml) added. The mixture was stirred with ice-cooling for 4 h, poured onto saturated potassium carbonate (20 ml) and extracted with dichloromethane. The combined extracts were dried (MgSO4) and solvent removed at reduced pressure to give the title compound (0.10 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07470710B2
Source datasetuspto-grants-2008_12
ORD IDord-afb8a15e883a4d33b38e9b1a3ffd7700
Source noteuspto-grants-2008_12