1-Boc-2-Piperidineacetic Acid → HCID 23146257, compound

HRID 2377999Notes

Reaction equation

HRID 2377999 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([NH2:8])[C:3]=1[NH2:9].C(OC([N:17]1[CH2:22][CH2:21][CH2:20][CH2:19][CH:18]1[CH2:23][C:24](O)=O)=O)(C)(C)C>>[Br:1][C:2]1[C:3]2[N:9]=[C:24]([CH2:23][CH:18]3[CH2:19][CH2:20][CH2:21][CH2:22][NH:17]3)[NH:8][C:4]=2[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 50585361-Boc-2-Piperidineacetic AcidHCID 124898393-Bromobenzene-1,2-diamine

Product 1

HCID 23146257HCID 23146257, compound

Procedure

The title compound was prepared using the method of Description 18 from 3-bromobenzene-1,2-diamine (0.50 g, 2.7 mmol) and 2-carboxymethyl-piperidine-1-carboxylic acid tert-butyl ester (0.65 g, 2.7 mmol), as a pale brown amorphous solid (0.70 g, 88%)

Sources & evidence

ORD record
ord-1f4f85b353df497f933f0ac64bee0f0e
Source dataset
uspto-grants-2008_12
Patent number
US07470710B2

Reaction notes

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